| DRUG (BRAND NAME) |
THERAPEUTIC INDICATION |
TYPICAL DOSE
and ROUTE* FOR
1000 LB (450 KG)
HORSE |
ELIMINATION
HALF-LIFE |
DETECTION LIMIT
(SOURCE OF
INFORMATION) |
| Tranquilizers/Sedatives |
| acepromazine (Atravet®, PromAce®) |
Tranquilizer used for calming horses. Has
no pain-relieving action. |
25 mg IV, IM
30 mg IM
50 mg Orally |
3 hr (IV)
6 hr (Orally) |
36 hr (Canada)
120 hr (AAEP)
72 hr (Australia) |
| butorphanol (Torbugesic®) |
Sedative with pain-relieving action, used
frequently to treat colic in horses. |
5 mg IV |
4 hr |
72 hr (Canada) |
| dantrolene (Dantrium®) |
Muscle relaxant used in horses with
myopathies ("tying-up"). |
1 gram Orally |
2 hr |
36 hr (Canada) |
| detomidine (Dormosedan®) |
Sedative with pain-relieving action, used
frequently to treat colic in horses. |
5 mg IV
|
1 hr |
48 hr (Australia)
72 hr (Canada) |
| guaifenesin (Guailaxin®, Gecolate®) |
Muscle relaxant used in horses with
myopathies ("tying-up"). |
2 gram IV, Orally |
1.5 hr |
24 hr (Canada)
48 hr (Australia) |
| methocarbamol (Robaxin®) |
Muscle relaxant used in horses with
myopathies ("tying-up"). |
5 grams IV, Orally |
1 hr |
24 hr (Canada) |
| romifidine (Sedivet®) |
Sedative with pain-relieving action, used
frequently to treat colic in horses. |
30 mg IV |
NA** |
48 hr (Australia) |
| Anti-inflammatories/Pain Relievers |
| aspirin |
Orallyor pain-reliever in the horse.
Sometimes used to treat periodic
ophthalmia ("moon blindness"), laminitis,
and colic due to parasite damage. |
11.7 grams Orally |
1 hr |
24 hr (Canada) |
| dimethylsulfoxide (DMSO)
|
Applied topically as an anti-inflammatory
agent, given IV to treat myopathies and
increase urination. |
19.8 grams topically |
9 hr |
36 hr (Canada)
72 hr (AAEP) |
| 450 mg IV |
|
96 hr (AAEP) |
| dipyrone (Novin®) |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
10 grams IV, IM |
NA |
120 hr (Canada)
15 days (ELISA test -
AAEP) |
| flunixin meglumine (Banamine®) |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
450 mg IV, Orally |
1.6 hr |
72 hr (Canada)
72 hr (Australia)
15 days (ELISA - AAEP) |
| ketoprofen (Ketofen®, Anafen®) |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
1 gram IV |
1.5 hr |
48 hr (Canada)
72 hr (Australia, AAEP) |
| lidocaine (Xylocaine®) |
Local anesthetic used to block nerves. |
150 mg SC |
1 hr |
24 hr (Canada) |
| meclofenamic acid (Arquel®) |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
1 gram Orally |
8 hr |
48 hr (Canada)
72 hr (Australia) |
| mepivicaine (Carbocaine®) |
Local anesthetic used to block nerves. |
300 mg SC, IA |
3 hr |
48 hr (Canada, Australia) |
| naproxen (Equiproxen, Aleeve®) |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
2 grams Orally |
4 hr |
120 hr (Canada) |
| phenylbutazone ("Bute") |
Nonsteroidal anti-inflammatory drug used
to treat colic and musculoskeletal pain and
inflammation. |
3 grams, IV, Orally |
11 hr |
96 hr (Canada)
120 hr (Australia) |
| procaine (Novocaine®) |
Local anesthetic used to block nerves. |
200 mg SC |
2 hr IM
1 hr SC |
48 hr (Canada) |
| procaine penicillin G |
Combined with penicillin to make the
antibiotic slowly absorbed from the
injection site, to give it a long duration of
antibacterial action. |
4 million International
Units IM |
10 hr |
425 hr (Canada) |
| Corticosteroids |
| betamethasone (Betasone®, Celestone®) |
Anti-inflammatory; allergic reactions. |
35 mg IM |
NA |
24 hr (Canada)
> 7 days (Australia) |
| dexamethasone (Azium®) |
Anti-inflammatory; allergic reactions. |
25 mg IV, IM
10 mg Orally |
4 hr |
24 hr (Canada)
48 hr (Australia)
144 hr (ELISA - AAEP) |
| flumethasone (Flucort®) |
Anti-inflammatory; allergic reactions. |
5 mg IV, IM |
NA |
24 hr (Canada) |
| isoflupredone (Predef 2X®) |
Anti-inflammatory; allergic reactions. |
24 mg IM |
NA |
48 hr (Canada) |
| methylprednisolone acetate (Depo-Medrol®) |
Anti-inflammatory; allergic reactions. |
200 mg IA, IM |
9 days |
96 hr (Canada)
222 hr (ELISA - AAEP)
> 45 days (Australia) |
| prednisolone |
Anti-inflammatory; allergic reactions. |
150 mg IV |
1.65 hr |
24 hr (Canada) |
| prednisone |
Anti-inflammatory; allergic reactions. |
1 gram Orally |
2 hr |
24 hr (Canada) |
| triamcinolone (Vetalog®) |
Anti-inflammatory; allergic reactions. |
24 mg IM |
2 hr |
24 hr (Canada)
15 days (Australia) |
| |
|
30 mg IA |
|
72 hr (Australia)
96 hr (Canada) |
| Miscellaneous Drugs |
| aminophylline |
Opens airways in horses with "heaves". |
1.5 grams IV |
NA |
96 hr (Canada) |
| theophylline |
Opens airways in horses with "heaves". |
6 grams Orally |
NA |
>7 days (Australia) |
| clenbuterol (Ventipulmin®) |
Opens airways in horses with "heaves". |
0.4 mg Orally |
NA |
72 hr (Canada) |
| dembrexine (Sputolysin®) |
Expectorant for horses with "heaves". |
150 mg Orally |
NA |
72 hr (Canada) |
| diphenhydramine (Benadryl®) |
Antihistamine. |
500 mg Orally |
NA |
48 hr (Canada, Australia) |
| isoxuprine (Vasodilan®) |
Dilates blood vessels, used for treatment of
navicular disease. |
300 mg Orally |
3 hr |
36 hr (Canada)
weeks-months (ELISA -
AAEP) |
* IV - intravenous, IM - Intramuscular, SC - Subcutaneous, IA - Intra-articular (into the joint)
** No information available.
